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[Immunomorphological reaction of organism in prosthetic plasty of the anterior abdominal wall using polypropylene mesh in patients, suffering postoperative abdominal hernia].
- Source :
-
Klinichna khirurhiia [Klin Khir] 2009 Feb (2), pp. 22-4. - Publication Year :
- 2009
-
Abstract
- Clinico-experimental studying the immunomorphological reactions variants in the prosthesis of anterior abdominal wall using synthetic polypropylene mesh was conducted. In 70 patients, operated on for postoperative hernia of abdominal wall using "on lay" method and the immune state were studied up by means of investigation of proinflammatory and anti-inflammatory cytokines content, in part, of tumor necrosis factor-alpha; (TNF-alpha), IL-8, IL-4. Morphological investigations were conducted in experiment on 100 the Vistar line mices, there were studied reactions of fibroblasts, macrophages, lymphocytes and leucocytes. The results of the immunological and morphological reactions on polypropylene obtained trust the necessity of differentiated approach application for the choice of the synthetic prosthesis kind, taking into account its biocompatibility, physical properties, the hernial defect size etc.
- Subjects :
- Abdominal Wall surgery
Adult
Aged
Animals
Biocompatible Materials adverse effects
Cell Count
Female
Fibroblasts drug effects
Fibroblasts pathology
Hernia, Abdominal diagnostic imaging
Hernia, Abdominal pathology
Humans
Interleukin-4 immunology
Interleukin-8 immunology
Male
Mice
Mice, Inbred Strains
Middle Aged
Postoperative Complications diagnostic imaging
Postoperative Complications pathology
Treatment Outcome
Tumor Necrosis Factor-alpha immunology
Ultrasonography
Young Adult
Abdominal Wall pathology
Hernia, Abdominal immunology
Hernia, Abdominal surgery
Polypropylenes adverse effects
Postoperative Complications immunology
Postoperative Complications surgery
Surgical Mesh adverse effects
Subjects
Details
- Language :
- Russian
- ISSN :
- 0023-2130
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Klinichna khirurhiia
- Publication Type :
- Academic Journal
- Accession number :
- 19673112