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Smooth(ing) muscle differentiation by microRNAs.

Authors :
Neppl RL
Wang DZ
Source :
Cell stem cell [Cell Stem Cell] 2009 Aug 07; Vol. 5 (2), pp. 130-2.
Publication Year :
2009

Abstract

In a recent report in Nature, Cordes et al. (2009) demonstrate that miR-143 and miR-145 modulate smooth muscle cell (SMC) plasticity in part by regulating key transcription factors involved in SMC fate determination.

Subjects

Subjects :
Animals
Humans
Myocytes, Smooth Muscle cytology
Cell Differentiation
Heterogeneous-Nuclear Ribonucleoprotein Group A-B metabolism
MicroRNAs metabolism
Myocytes, Smooth Muscle metabolism
Nuclear Proteins metabolism
Repressor Proteins metabolism
Serum Response Factor metabolism
Trans-Activators metabolism

Details

Language :
English
ISSN :
1875-9777
Volume :
5
Issue :
2
Database :
MEDLINE
Journal :
Cell stem cell
Publication Type :
Academic Journal
Accession number :
19664984
Full Text :
https://doi.org/10.1016/j.stem.2009.07.004
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