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Base and copper(I) catalyzed Mannich, alkyne hydroamination cascades for the direct synthesis of 2-methylenepyrrolidines.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2009 Jul 14 (26), pp. 3916-8. Date of Electronic Publication: 2009 Jun 01. - Publication Year :
- 2009
-
Abstract
- An efficient, simple-to-perform, one-pot reaction cascade to 2-methylenepyrrolidines from p-toluenesulfonyl protected imines and propargylated malonates under a combination of base and copper(I) catalysis is reported.
Details
- Language :
- English
- ISSN :
- 1359-7345
- Issue :
- 26
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 19662251
- Full Text :
- https://doi.org/10.1039/b905629g