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Actin-based protrusions: promoters or inhibitors of cancer invasion?
- Source :
-
Cancer cell [Cancer Cell] 2009 Jul 07; Vol. 16 (1), pp. 5-7. - Publication Year :
- 2009
-
Abstract
- In a recent issue of Cell, Silva and colleagues reported the identification of CYFIP1, a member of the actin-assembly-promoting Scar/WAVE complex, as an invasion suppressor in epithelial cancers. This study challenges ideas about the role of actin in cancer invasion.
- Subjects :
- Animals
Cell Line, Tumor
Hedgehog Proteins antagonists & inhibitors
Hedgehog Proteins physiology
Humans
Magnetic Resonance Imaging
Mice
Mutation
Neoplasm Invasiveness
Pancreatic Neoplasms epidemiology
Pancreatic Neoplasms genetics
Pancreatic Neoplasms mortality
Perfusion
Signal Transduction
Survival Analysis
United States epidemiology
Veratrum Alkaloids therapeutic use
Actins metabolism
Pancreatic Neoplasms pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1878-3686
- Volume :
- 16
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Cancer cell
- Publication Type :
- Academic Journal
- Accession number :
- 19573806
- Full Text :
- https://doi.org/10.1016/j.ccr.2009.06.009