Back to Search Start Over

[Lopinavir/ritonavir monotherapy as a simplification strategy in antiretroviral therapy in clinical practice].

Authors :
Moltó J
Clotet B
Source :
Enfermedades infecciosas y microbiologia clinica [Enferm Infecc Microbiol Clin] 2008 Dec; Vol. 26 Suppl 16, pp. 24-6.
Publication Year :
2008

Abstract

Although guidelines for the treatment of HIV-infected patients recommend triple drug antiretroviral therapy, because of the toxicity of these regimens, the complexity of treatment and its costs, other therapeutic options are desirable. Several clinical trials have shown that lopinavir/ritonavir (LPV/r) as a simplification strategy in antiretroviral therapy in HIV-infected patients who maintain suppression of viral replication while receiving conventional treatment regimens is safe and is associated with less toxicity than that due to prolonged exposure to protease inhibitors and nucleoside analogs. The present review summarizes the main results of the various retrospective studies on LPV/r as a simplification strategy of antiretroviral therapy in daily clinical practice.

Details

Language :
Spanish; Castilian
ISSN :
0213-005X
Volume :
26 Suppl 16
Database :
MEDLINE
Journal :
Enfermedades infecciosas y microbiologia clinica
Publication Type :
Academic Journal
Accession number :
19572441
Full Text :
https://doi.org/10.1016/s0213-005x(08)76607-2