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Excessive iodine intake and ultrasonographic thyroid abnormalities in schoolchildren.

Authors :
Duarte GC
Tomimori EK
de Camargo RY
Catarino RM
Ferreira JE
Knobel M
Medeiros-Neto G
Source :
Journal of pediatric endocrinology & metabolism : JPEM [J Pediatr Endocrinol Metab] 2009 Apr; Vol. 22 (4), pp. 327-34.
Publication Year :
2009

Abstract

High nutritional levels of iodine may induce a higher prevalence of autoimmune thyroiditis, hypothyroidism, goiter, as well as hyperthyroidism, mostly in the elderly. This study assessed thyroid volume and ultrasonographic abnormalities as well as urinary iodine excretion (UIE) in 964 schoolchildren living in an iodine-sufficient area in southern Brazil. Thyroid volume correlated with age and body surface area in boys and girls. In 76.8% of the children, UIE was above 300 microg/l, with higher levels among boys compared to girls (484.2 microg/l vs 435.3 microg/l, p < 0.001). Thyroid abnormalities detected by ultrasonography included hemiagenesis (0.5%), nodules (0.2%), cysts (0.7%), and hypoechogenicity (11.7%). Goiter was present in 1.9% of the children. Hypoechogenicity, a relevant marker of autoimmune thyroiditis, was the most common abnormality found in our study, and this may be linked to excessive iodine intake.

Details

Language :
English
ISSN :
0334-018X
Volume :
22
Issue :
4
Database :
MEDLINE
Journal :
Journal of pediatric endocrinology & metabolism : JPEM
Publication Type :
Academic Journal
Accession number :
19554806
Full Text :
https://doi.org/10.1515/jpem.2009.22.4.327