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Relations between protein intake and blood pressure in Japanese men and women: the Circulatory Risk in Communities Study (CIRCS).
- Source :
-
The American journal of clinical nutrition [Am J Clin Nutr] 2009 Aug; Vol. 90 (2), pp. 377-84. Date of Electronic Publication: 2009 Jun 10. - Publication Year :
- 2009
-
Abstract
- Background: An inverse association between protein intake and blood pressure has been reported in Western countries. However, the evidence is limited for Asians, whose protein sources are different from those in Western populations.<br />Objectives: The objective was to examine the association between protein intake and blood pressure in Japanese adults.<br />Methods: We conducted a population-based, cross-sectional study of 7585 subjects (3499 men and 4086 women) from 40 to 69 y of age living in 5 communities in Japan. Dietary intakes of total, animal, and plant protein were estimated by a single 24-h dietary recall. We then examined the associations between dietary intake of those proteins and blood pressure after adjustment for age, sex, community, body mass index, antihypertensive medication use, ethanol intake, smoking, and dietary intakes of sodium, potassium, and calcium.<br />Results: After adjustment for cardiovascular disease risk factors, a 25.5-g/d increment in total protein intake was associated with a decrease in systolic blood pressure of 1.14 mm Hg (P < 0.001) and in diastolic blood pressure of 0.65 mm Hg (P < 0.001), and a 19.9-g/d increment in animal protein intake was associated with a decrease in systolic blood pressure of 1.09 mm Hg (P < 0.001) and in diastolic blood pressure of 0.41 mm Hg (P = 0.003). A 13.1-g/d increment in plant protein intake was associated with a decrease in diastolic blood pressure of 0.57 mm Hg (P < 0.001). Further adjustment for nutritional factors weakened these associations, but the inverse associations of total protein intake with diastolic blood pressure and of animal protein intake with systolic blood pressure remained statistically significant.<br />Conclusion: Total and animal protein intakes were inversely associated with blood pressure in Japanese adults.
- Subjects :
- Adult
Age Distribution
Aged
Calcium, Dietary administration & dosage
Cohort Studies
Cross-Sectional Studies
Diastole
Dose-Response Relationship, Drug
Female
Health Surveys
Humans
Hypertension etiology
Japan epidemiology
Male
Meat
Mental Recall
Middle Aged
Multivariate Analysis
Plant Proteins, Dietary administration & dosage
Potassium, Dietary administration & dosage
Seafood
Sex Distribution
Sodium, Dietary administration & dosage
Systole
Blood Pressure drug effects
Blood Pressure physiology
Dietary Proteins administration & dosage
Hypertension epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1938-3207
- Volume :
- 90
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The American journal of clinical nutrition
- Publication Type :
- Academic Journal
- Accession number :
- 19515740
- Full Text :
- https://doi.org/10.3945/ajcn.2008.27109