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[Oral insulin preparations for the regulation of the glucose level in the blood].

Authors :
Valuev LI
Sytov GA
Starosel'tseva LK
Valuev IL
Vanchugova LV
Valueva TA
Ul'ianova MV
Platé NA
Source :
Biomeditsinskaia khimiia [Biomed Khim] 2009 Mar-Apr; Vol. 55 (2), pp. 195-200.
Publication Year :
2009

Abstract

Oral administration of diluted solutions of insulin results in the absorption of the hormone into bloodstream. After oral administration of diluted insulin solutions to healthy volunteers and animals with experimental diabetes insulin does not undergo hydrolytic degradation under the action of proteolytic enzymes and its absorption is sufficient to produce the hypoglycemic effect. This approach gives a chance of creating of novel strategy for diabetes treatment.

Details

Language :
Russian
ISSN :
2310-6972
Volume :
55
Issue :
2
Database :
MEDLINE
Journal :
Biomeditsinskaia khimiia
Publication Type :
Academic Journal
Accession number :
19507343