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[Structural changes in the nuclei of human lymphocytes under the effects of ionizing radiation within the range of doses that cause the adaptive response].
- Source :
-
Radiobiologiia [Radiobiologiia] 1991 Jul-Aug; Vol. 31 (4), pp. 606-11. - Publication Year :
- 1991
-
Abstract
- Low-level radiation either from external, or from incorporated sources is shown to cause a non-monotonous change in some intranuclear parameters of human peripheral blood lymphocytes. For instance, radiation induces changes in the parameters that characterize the location of perecentromeric regions within the interphase nucleus and a non-monotonous increase in nuclear sizes. The exposure to doses exceeding 5 cGy impairs the relationship between the nuclear sizes and location therein of the perecentromeric regions of interphase chromosomes which exist in the control and after exposure to 2.5 cGy. Differences between the dose ranges of 1.5-3.5 and 17-25 cGy are manifested by the kinetics of restoration of the pattern of distribution of lymphocyte nuclear sizes.
- Subjects :
- Adaptation, Biological
Adult
Cell Nucleus drug effects
Centromere radiation effects
Chromosomes radiation effects
Humans
In Vitro Techniques
Interphase
Lymphocytes drug effects
Male
Middle Aged
Radiation, Ionizing
Thymidine pharmacology
Cell Nucleus radiation effects
Lymphocytes radiation effects
Radiation Dosage
Subjects
Details
- Language :
- Russian
- ISSN :
- 0033-8192
- Volume :
- 31
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Radiobiologiia
- Publication Type :
- Academic Journal
- Accession number :
- 1947036