Inhibitors paradoxically prime kinases.

Authors :: Frye SV
Johnson GL
Source :: Nature chemical biology [Nat Chem Biol] 2009 Jul; Vol. 5 (7), pp. 448-9.
Publication Year :: 2009

Subjects :: Enzyme Activation
Phosphorylation
Protein Binding
Protein Conformation
Protein Kinase Inhibitors chemistry
Protein Kinases chemistry
Small Molecule Libraries chemistry
Drug Design
Protein Kinase Inhibitors pharmacology
Protein Kinases metabolism
Small Molecule Libraries pharmacology

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