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[Analysis of distribution, drug resistance and risk factors of pathogens isolated from septicemic patients].
- Source :
-
Nan fang yi ke da xue xue bao = Journal of Southern Medical University [Nan Fang Yi Ke Da Xue Xue Bao] 2009 May; Vol. 29 (5), pp. 990-2. - Publication Year :
- 2009
-
Abstract
- Objective: To investigate distribution, drug resistance and risk factors of pathogens isolated from septicemic patients in a hospital in the past 6 years.<br />Methods: Most of the bacterial isolates were identified with BD Phoenix, and a few isolates were identified manually and with K-B method. Candida isolates were identified with color display plates and K-B method. WHONET5.4 software was used for analysis.<br />Results: The common bacteria isolated form the blood included E. coli, P. aeruginosa, K. pneumoniae, and S. aureu. The gram-negative bacillus from the blood exhibited relatively low resistance to such antibiotics as cefoperazone/sulbactam, imipenem, amikacin, piperacillin/tazobactam, and ceftazidime, and the incidences of E.coli and K. pneumoniae isolates producing extended spectrum beta-lactamase (ESBLs) ranged between 33.3% and 34.9% and between 32.9% and 36.0%, respectively. The gram-positive coccus from blood showed a sensitivity rate of 100.0% to vancomycin and low resistant rates to amikacin and chloramphenicol; the methicillin-resistant rates of S. aureu and coagulase-negative staphylococcus were 26.9%-35.5% and 72.7%-74.3%, respectively. The risk factors of septicemia included hospital stay for over 5 days, venous catheterization, surgeries, puncture, oxygen therapy, urine tract catheterization, and chemotherapy.<br />Conclusion: Blood culture can be of importance in patients with septicemia, and the use of antibiotics should be carefully weighed according to the results of bacterial culture and sensitivity tests of the pathogens isolated from the blood.
- Subjects :
- Adolescent
Adult
Aged
Candida albicans drug effects
Candida albicans isolation & purification
Child
Child, Preschool
Escherichia coli drug effects
Escherichia coli isolation & purification
Female
Gram-Negative Bacteria drug effects
Humans
Infant
Klebsiella pneumoniae drug effects
Klebsiella pneumoniae isolation & purification
Male
Microbial Sensitivity Tests
Middle Aged
Pseudomonas aeruginosa drug effects
Pseudomonas aeruginosa isolation & purification
Risk Factors
Staphylococcus aureus drug effects
Staphylococcus aureus isolation & purification
Young Adult
Drug Resistance, Bacterial
Gram-Negative Bacteria isolation & purification
Sepsis microbiology
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1673-4254
- Volume :
- 29
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Nan fang yi ke da xue xue bao = Journal of Southern Medical University
- Publication Type :
- Academic Journal
- Accession number :
- 19460728