Identification of a polyketide synthase coding sequence specific for anatoxin-a-producing Oscillatoria cyanobacteria.

Authors :: Cadel-Six S
Iteman I
Peyraud-Thomas C
Mann S
Ploux O
Méjean A
Source :: Applied and environmental microbiology [Appl Environ Microbiol] 2009 Jul; Vol. 75 (14), pp. 4909-12. Date of Electronic Publication: 2009 May 15.
Publication Year :: 2009
Abstract: We report the identification of a sequence from the genome of Oscillatoria sp. strain PCC 6506 coding for a polyketide synthase. Using 50 axenic cyanobacteria, we found this sequence only in the genomes of Oscillatoria strains producing anatoxin-a or homoanatoxin-a, indicating its likely involvement in the biosynthesis of these toxins.

Subjects :: Bacterial Toxins metabolism
Bridged Bicyclo Compounds, Heterocyclic metabolism
Cyanobacteria Toxins
DNA, Bacterial chemistry
DNA, Bacterial genetics
Molecular Sequence Data
Molecular Structure
Oscillatoria genetics
Sequence Analysis, DNA
Oscillatoria enzymology
Polyketide Synthases genetics
Tropanes metabolism

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