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[Effect of cyclopentyladenosine on the orientation, exploratory, and emotional behavior of rats with model brain injury].

Authors :
Sufianova GZ
Sufianov AA
Shapkin AG
Usov LA
Source :
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2009 Mar-Apr; Vol. 72 (2), pp. 20-3.
Publication Year :
2009

Abstract

Effects of a local compression brain injury and the preventive application of cyclopentyladenosine (CPA) on the behavior of rats in the open field test was investigated. It is established that the local injury of a parietal cortex causes intensification of the orientation--research behavior and an increase in the emotional stress in rats. A protective action of CPA was manifested by a decrease in the expressiveness and duration of disturbances in the emotional and orientation--research behavior of animals in the open field test.

Details

Language :
Russian
ISSN :
0869-2092
Volume :
72
Issue :
2
Database :
MEDLINE
Journal :
Eksperimental'naia i klinicheskaia farmakologiia
Publication Type :
Academic Journal
Accession number :
19441722