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[Effect of cyclopentyladenosine on the orientation, exploratory, and emotional behavior of rats with model brain injury].
- Source :
-
Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2009 Mar-Apr; Vol. 72 (2), pp. 20-3. - Publication Year :
- 2009
-
Abstract
- Effects of a local compression brain injury and the preventive application of cyclopentyladenosine (CPA) on the behavior of rats in the open field test was investigated. It is established that the local injury of a parietal cortex causes intensification of the orientation--research behavior and an increase in the emotional stress in rats. A protective action of CPA was manifested by a decrease in the expressiveness and duration of disturbances in the emotional and orientation--research behavior of animals in the open field test.
- Subjects :
- Adenosine pharmacology
Animals
Disease Models, Animal
Injections, Intraventricular
Male
Rats
Adenosine analogs & derivatives
Adenosine A1 Receptor Antagonists
Behavior, Animal drug effects
Brain Injuries psychology
Emotions drug effects
Exploratory Behavior drug effects
Orientation drug effects
Subjects
Details
- Language :
- Russian
- ISSN :
- 0869-2092
- Volume :
- 72
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Eksperimental'naia i klinicheskaia farmakologiia
- Publication Type :
- Academic Journal
- Accession number :
- 19441722