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Molecular and biochemical pharmacology of the histamine H4 receptor.
- Source :
-
British journal of pharmacology [Br J Pharmacol] 2009 May; Vol. 157 (1), pp. 14-23. - Publication Year :
- 2009
-
Abstract
- The elucidation of the human genome has had a major impact on histamine receptor research. The identification of the human H4 receptor by several groups has been instrumental for a new appreciation of the role of histamine in the modulation of immune function. In this review, we summarize the historical developments and the molecular and biochemical pharmacology of the H4 receptor.
- Subjects :
- Animals
Binding Sites
Humans
Ligands
Models, Molecular
Phylogeny
Protein Conformation
Receptors, Histamine H4
Species Specificity
Receptors, G-Protein-Coupled agonists
Receptors, G-Protein-Coupled antagonists & inhibitors
Receptors, G-Protein-Coupled genetics
Receptors, G-Protein-Coupled physiology
Receptors, Histamine genetics
Receptors, Histamine physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1476-5381
- Volume :
- 157
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- British journal of pharmacology
- Publication Type :
- Academic Journal
- Accession number :
- 19413568
- Full Text :
- https://doi.org/10.1111/j.1476-5381.2009.00250.x