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Zn/InCl(3)-mediated pinacol cross-coupling reactions of aldehydes with alpha,beta-unsaturated ketones in aqueous media.

Authors :
Yang YS
Shen ZL
Loh TP
Source :
Organic letters [Org Lett] 2009 May 21; Vol. 11 (10), pp. 2213-5.
Publication Year :
2009

Abstract

A zinc/indium chloride-mediated pinacol cross-coupling reaction between aldehyde and alpha,beta-unsaturated ketone in aqueous media was developed. The 1,2-diols were obtained in moderate to good yields with up to 93:7 diastereoselectivity.

Details

Language :
English
ISSN :
1523-7052
Volume :
11
Issue :
10
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
19385662
Full Text :
https://doi.org/10.1021/ol900619d