Back to Search Start Over

Fallen immortals.

Authors :
Swigut T
Wysocka J
Source :
Cell [Cell] 2009 Apr 17; Vol. 137 (2), pp. 203-5.
Publication Year :
2009

Abstract

The memory of somatic cell gene expression is reset in the germline in a process that is accompanied by dramatic changes in chromatin modifications. In this issue, Katz et al. (2009) show that the histone demethylase Lsd1/Spr-5 may participate in this resetting process in the worm, thereby preventing a decline in germ cell epigenetic stability and viability over ensuing generations.

Subjects

Subjects :
Animals
Caenorhabditis elegans cytology
Caenorhabditis elegans metabolism
Caenorhabditis elegans Proteins genetics
Caenorhabditis elegans Proteins metabolism
Germ Cells metabolism
Histones metabolism
Oxidoreductases, N-Demethylating
Caenorhabditis elegans embryology
Epigenesis, Genetic
Germ Cells cytology

Details

Language :
English
ISSN :
1097-4172
Volume :
137
Issue :
2
Database :
MEDLINE
Journal :
Cell
Publication Type :
Academic Journal
Accession number :
19379684
Full Text :
https://doi.org/10.1016/j.cell.2009.04.008
Full Text Access
View/download PDF

Tools

Authors Abstract Subjects Details