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Assessment of bone perfusion with contrast-enhanced magnetic resonance imaging.
- Source :
-
The Orthopedic clinics of North America [Orthop Clin North Am] 2009 Apr; Vol. 40 (2), pp. 249-57. - Publication Year :
- 2009
-
Abstract
- Osteoarthritis and avascular necrosis are common clinical entities with unknown origins. Recently, vascular changes were implicated in the pathogenesis of both conditions. This article discusses the use of novel noninvasive imaging techniques as a means of assessing bone perfusion and quantifying differences seen in osteoarthritis and avascular necrosis. Review of our human data suggests that the MRI contrast dye is retained for longer periods of time, suggesting decreased perfusion out of regions of osteoarthritis and avascular necrosis. Use of such a noninvasive measure of assessing bone perfusion could be useful in the diagnosis, prevention, and treatment of not only osteoarthritis and avascular necrosis but also other entities that affect the musculoskeletal system.
- Subjects :
- Adult
Aged
Aged, 80 and over
Animals
Bone Marrow Diseases complications
Diagnosis, Differential
Disease Models, Animal
Edema complications
Femur Head pathology
Follow-Up Studies
Gadolinium DTPA administration & dosage
Guinea Pigs
Humans
Injections, Intravenous
Knee Joint pathology
Middle Aged
Osteoarthritis, Hip complications
Osteoarthritis, Knee complications
Osteonecrosis complications
Syndrome
Young Adult
Bone Marrow Diseases diagnosis
Contrast Media administration & dosage
Edema diagnosis
Magnetic Resonance Imaging methods
Osteoarthritis, Hip diagnosis
Osteoarthritis, Knee diagnosis
Osteonecrosis diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1558-1373
- Volume :
- 40
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The Orthopedic clinics of North America
- Publication Type :
- Academic Journal
- Accession number :
- 19358910
- Full Text :
- https://doi.org/10.1016/j.ocl.2008.12.003