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2-Arylbenzofuran Derivatives from Morus cathayana.
- Source :
-
Journal of natural products [J Nat Prod] 2009 May 22; Vol. 72 (5), pp. 966-8. - Publication Year :
- 2009
-
Abstract
- Four new 2-arylbenzofuran derivatives, cathafurans A (1), B (2), C (3), and D (4), were isolated from the stem bark of Morus cathayana. Their structures were determined by spectroscopic methods. Compounds 2 and 3 exhibited moderate activities against five human cancer cell lines, with IC(50) values ranging from 6.17 to 9.60 microg/mL.
- Subjects :
- Antineoplastic Agents, Phytogenic chemistry
Antineoplastic Agents, Phytogenic pharmacology
Benzofurans chemistry
Benzofurans pharmacology
Drug Screening Assays, Antitumor
Drugs, Chinese Herbal chemistry
Drugs, Chinese Herbal pharmacology
Humans
Inhibitory Concentration 50
Molecular Structure
Nuclear Magnetic Resonance, Biomolecular
Plant Bark chemistry
Antineoplastic Agents, Phytogenic isolation & purification
Benzofurans isolation & purification
Drugs, Chinese Herbal isolation & purification
Morus chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1520-6025
- Volume :
- 72
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Journal of natural products
- Publication Type :
- Academic Journal
- Accession number :
- 19338315
- Full Text :
- https://doi.org/10.1021/np800789y