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Stabilizing guanosine-sterol ion channels with a carbamate to urea modification in the linker.
- Source :
-
Organic letters [Org Lett] 2009 Apr 02; Vol. 11 (7), pp. 1599-602. - Publication Year :
- 2009
-
Abstract
- The use of a bis-urea lithocholamide linker within a guanosine-sterol dimer resulted in formation of large and stable ion channels. The channels were longer-lived than those formed by the corresponding bis-carbamate.
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 11
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 19275224
- Full Text :
- https://doi.org/10.1021/ol9002477