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Reduction of collagen biosynthesis in blood vessels and other tissues by reserpine and hypophysectomy.

Authors :
Ooshima A
Fuller GC
Cardinale GJ
Spector S
Udenfriend S
Source :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 1977 Feb; Vol. 74 (2), pp. 777-9.
Publication Year :
1977

Abstract

Synthesis of collagen in the vasculature and other tissues of normotensive rats is markedly reduced by reserpine. Hypophysectomy produces similar effects. The effects of reserpine on collagen biosynthesis may be mediated through the hypothalamus.

Details

Language :
English
ISSN :
0027-8424
Volume :
74
Issue :
2
Database :
MEDLINE
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
191825
Full Text :
https://doi.org/10.1073/pnas.74.2.777