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A case of pulmonary cryptococcosis followed by pleuritis in an apparently immunocompetent patient during fluconazole treatment.
- Source :
-
Medical mycology [Med Mycol] 2008 Sep; Vol. 46 (6), pp. 595-9. - Publication Year :
- 2008
-
Abstract
- Cryptococcal pleuritis is rare in individuals with no underlying disease. We report a case of pulmonary cryptococcosis followed by pleuritis in a patient on fluconazole treatment. Biopsy of the pleura revealed a granuloma and a cryptococcal body, while PCR and sequence analysis of extracted DNA from the pleura proved the presence of Cryptococcus species, most likely C. neoformans. Voriconazole with flucytosine and drainage of the pleural effusion were effective in treating the patient.
- Subjects :
- Adult
Base Sequence
Cryptococcosis drug therapy
Cryptococcus neoformans genetics
Humans
Lung Diseases, Fungal drug therapy
Male
Molecular Sequence Data
Pleurisy immunology
Pleurisy microbiology
Sequence Alignment
Cryptococcosis microbiology
Cryptococcus neoformans isolation & purification
Fluconazole therapeutic use
Immunocompromised Host drug effects
Lung Diseases, Fungal microbiology
Pleurisy drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 1369-3786
- Volume :
- 46
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Medical mycology
- Publication Type :
- Academic Journal
- Accession number :
- 19180728
- Full Text :
- https://doi.org/10.1080/13693780802074494