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Wegener's granulomatosis presenting as acute systemic vasculitis following 20 years of limited tracheobronchial disease.
- Source :
-
The Journal of laryngology and otology [J Laryngol Otol] 2009 Dec; Vol. 123 (12), pp. 1375-7. Date of Electronic Publication: 2009 Jan 28. - Publication Year :
- 2009
-
Abstract
- Objective: We report a patient with a 20-year history of apparently idiopathic airways stenoses, who presented with an antineutrophil cytoplasmic antibody (ANCA) associated, acute, systemic vasculitis with necrotising glomerulonephritis, subsequently diagnosed as Wegener's granulomatosis.<br />Methods: We present a case report and a review of the world literature on airway stenosis in Wegener's granulomatosis.<br />Results: To our knowledge, this is the first report of Wegener's granulomatosis manifesting as local airway disease for such a prolonged period, before transforming into a systemic vasculitis.<br />Conclusions: This case highlights the need for physicians to be alert to the possibility of Wegener's granulomatosis as a cause of apparently idiopathic airway stenosis, and to be aware that systemic disease may occur in very long-standing, limited Wegener's granulomatosis.
Details
- Language :
- English
- ISSN :
- 1748-5460
- Volume :
- 123
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- The Journal of laryngology and otology
- Publication Type :
- Academic Journal
- Accession number :
- 19175952
- Full Text :
- https://doi.org/10.1017/S002221510900454X