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Ménière's disease is a viral neuropathy.
- Source :
-
ORL; journal for oto-rhino-laryngology and its related specialties [ORL J Otorhinolaryngol Relat Spec] 2009; Vol. 71 (2), pp. 78-86. Date of Electronic Publication: 2009 Jan 10. - Publication Year :
- 2009
-
Abstract
- Morphological and clinical evidence supports a viral neuropathy in Ménière's disease (MD). Quantitative examination of 11 sectioned temporal bones (TBs) from 8 patients with a history of MD revealed a significant loss of vestibular ganglion cells in both the endolymph hydropic (EH) and non-EH ears. Transmission electron microscopy of vestibular ganglion cells excised from a patient with MD revealed viral particles enclosed in transport vesicles. Antiviral treatment controlled vertigo in 73 of 86 patients with vestibular neuronitis (85%) and 32 of 35 patients with MD (91%).<br /> (Copyright 2009 S. Karger AG, Basel.)
- Subjects :
- Aged
Aged, 80 and over
Endolymphatic Hydrops pathology
Endolymphatic Hydrops virology
Female
Humans
Male
Microscopy, Electron, Transmission
Middle Aged
Severity of Illness Index
Spiral Ganglion pathology
Spiral Ganglion virology
Vestibule, Labyrinth pathology
Vestibule, Labyrinth virology
Meniere Disease pathology
Meniere Disease virology
Vestibular Neuronitis pathology
Vestibular Neuronitis virology
Subjects
Details
- Language :
- English
- ISSN :
- 1423-0275
- Volume :
- 71
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- ORL; journal for oto-rhino-laryngology and its related specialties
- Publication Type :
- Academic Journal
- Accession number :
- 19142031
- Full Text :
- https://doi.org/10.1159/000189783