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Ménière's disease is a viral neuropathy.

Authors :
Gacek RR
Source :
ORL; journal for oto-rhino-laryngology and its related specialties [ORL J Otorhinolaryngol Relat Spec] 2009; Vol. 71 (2), pp. 78-86. Date of Electronic Publication: 2009 Jan 10.
Publication Year :
2009

Abstract

Morphological and clinical evidence supports a viral neuropathy in Ménière's disease (MD). Quantitative examination of 11 sectioned temporal bones (TBs) from 8 patients with a history of MD revealed a significant loss of vestibular ganglion cells in both the endolymph hydropic (EH) and non-EH ears. Transmission electron microscopy of vestibular ganglion cells excised from a patient with MD revealed viral particles enclosed in transport vesicles. Antiviral treatment controlled vertigo in 73 of 86 patients with vestibular neuronitis (85%) and 32 of 35 patients with MD (91%).<br /> (Copyright 2009 S. Karger AG, Basel.)

Details

Language :
English
ISSN :
1423-0275
Volume :
71
Issue :
2
Database :
MEDLINE
Journal :
ORL; journal for oto-rhino-laryngology and its related specialties
Publication Type :
Academic Journal
Accession number :
19142031
Full Text :
https://doi.org/10.1159/000189783