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Mycangimycin, a polyene peroxide from a mutualist Streptomyces sp.
- Source :
-
Organic letters [Org Lett] 2009 Feb 05; Vol. 11 (3), pp. 633-6. - Publication Year :
- 2009
-
Abstract
- A mutualist actinomycete of the southern pine beetle, Dendroctonus frontalis, produces a polyene peroxide with pronounced antifungal activity. Its structure, absolute configuration, and biological activity were determined by spectral analysis, chemical modification followed by the modified Mosher method, and growth inhibitory assays, respectively.
- Subjects :
- Acetates chemistry
Acetates pharmacology
Animals
Antifungal Agents chemistry
Antifungal Agents pharmacology
Coleoptera microbiology
Molecular Structure
Peroxides chemistry
Peroxides pharmacology
Pinus
Polyenes chemistry
Polyenes pharmacology
Acetates isolation & purification
Antifungal Agents isolation & purification
Peroxides isolation & purification
Polyenes isolation & purification
Streptomyces chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 11
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 19125624
- Full Text :
- https://doi.org/10.1021/ol802709x