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Genetic polymorphisms of 16 Y chromosomal STR loci in Korean population.
- Source :
-
Forensic science international. Genetics [Forensic Sci Int Genet] 2008 Mar; Vol. 2 (2), pp. e9-10. Date of Electronic Publication: 2007 Dec 21. - Publication Year :
- 2008
-
Abstract
- Allele frequencies and haplotypes of 16 Y chromosomal STR loci included in the AmpFlSTR((R)) Yfilertrade mark system were obtained from a sample of 526 unrelated Korean male individuals. A total of 478 haplotypes were observed in the 526 individuals studied, of which 440 were unique. The overall haplotype diversity for the 16 Y-STR loci was 0.9996, and the discrimination capacity was 0.9087. We found 13 atypical alleles, including null, duplicated and microvariant alleles. Microvariants have been characterized by sequencing, 14.1 allele at DYS458 showing the flanking site mutation, 13.1 and 15.2 allele at DYS385a/b showing changes in the repeat structure.
- Subjects :
- Alleles
DNA genetics
DNA isolation & purification
DNA Fingerprinting methods
Gene Frequency
Genetic Markers
Genotype
Haplotypes
Humans
Korea
Male
Nucleic Acid Amplification Techniques
Polymerase Chain Reaction
Quality Control
Asian People genetics
Chromosomes, Human, Y
Microsatellite Repeats genetics
Polymorphism, Genetic
Population Groups genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1878-0326
- Volume :
- 2
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Forensic science international. Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 19083802
- Full Text :
- https://doi.org/10.1016/j.fsigen.2007.11.001