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Imatinib-induced interstitial lung disease and sunitinib-associated intra-tumour haemorrhage.
- Source :
-
Hong Kong medical journal = Xianggang yi xue za zhi [Hong Kong Med J] 2008 Dec; Vol. 14 (6), pp. 495-8. - Publication Year :
- 2008
-
Abstract
- An ethnically Chinese patient with newly diagnosed metastatic gastro-intestinal stromal tumour initially treated with imatinib mesylate developed severe interstitial lung disease. As his condition improved after cessation of imatinib mesylate and treatment with corticosteroids, he was started on sunitinib malate. His clinical course was then unfortunately complicated with intra-tumour bleeding. This case report illustrates the dilemmas and complexities associated with treating patients with gastro-intestinal stromal tumours with the new tyrosine kinase inhibitors.
- Subjects :
- Benzamides
Gastrointestinal Stromal Tumors complications
Humans
Imatinib Mesylate
Male
Middle Aged
Sunitinib
Antineoplastic Agents adverse effects
Gastrointestinal Stromal Tumors drug therapy
Hemorrhage chemically induced
Indoles adverse effects
Lung Diseases, Interstitial chemically induced
Piperazines adverse effects
Pyrimidines adverse effects
Pyrroles adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1024-2708
- Volume :
- 14
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Hong Kong medical journal = Xianggang yi xue za zhi
- Publication Type :
- Academic Journal
- Accession number :
- 19060352