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African swine fever virus isolate, Georgia, 2007.
- Source :
-
Emerging infectious diseases [Emerg Infect Dis] 2008 Dec; Vol. 14 (12), pp. 1870-4. - Publication Year :
- 2008
-
Abstract
- African swine fever (ASF) is widespread in Africa but is rarely introduced to other continents. In June 2007, ASF was confirmed in the Caucasus region of Georgia, and it has since spread to neighboring countries. DNA fragments amplified from the genome of the isolates from domestic pigs in Georgia in 2007 were sequenced and compared with other ASF virus (ASFV) isolates to establish the genotype of the virus. Sequences were obtained from 4 genome regions, including part of the gene B646L that encodes the p72 capsid protein, the complete E183L and CP204L genes, which encode the p54 and p30 proteins and the variable region of the B602L gene. Analysis of these sequences indicated that the Georgia 2007 isolate is closely related to isolates belonging to genotype II, which is circulating in Mozambique, Madagascar, and Zambia. One possibility for the spread of disease to Georgia is that pigs were fed ASFV-contaminated pork brought in on ships and, subsequently, the disease was disseminated throughout the region.
- Subjects :
- African Swine Fever virology
Amino Acid Sequence
Animals
Base Sequence
Capsid Proteins genetics
Genotype
Georgia (Republic) epidemiology
Molecular Sequence Data
Phosphoproteins genetics
Sequence Analysis, DNA
Viral Proteins genetics
Viral Structural Proteins genetics
African Swine Fever epidemiology
African Swine Fever Virus classification
African Swine Fever Virus genetics
African Swine Fever Virus isolation & purification
Disease Outbreaks
Sus scrofa virology
Subjects
Details
- Language :
- English
- ISSN :
- 1080-6059
- Volume :
- 14
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Emerging infectious diseases
- Publication Type :
- Academic Journal
- Accession number :
- 19046509
- Full Text :
- https://doi.org/10.3201/eid1412.080591