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Self-reported global function among adult survivors of childhood lower-extremity bone tumors: a report from the Childhood Cancer Survivor Study (CCSS).
- Source :
-
Journal of cancer survivorship : research and practice [J Cancer Surviv] 2009 Mar; Vol. 3 (1), pp. 59-65. Date of Electronic Publication: 2008 Nov 22. - Publication Year :
- 2009
-
Abstract
- Introduction: Adult survivors of childhood lower-extremity bone tumors may experience physical and psychosocial late effects that impact physical performance, global function and quality of life. The identification of survivors at greatest risk for poor outcomes will inform potential intervention targets.<br />Methods: Study participants were selected from the Childhood Cancer Survivor Study (CCSS), a multi-institutional study of childhood cancer survivors. Adult survivors (n = 629) of either childhood onset osteosarcoma or Ewing's sarcoma, with a primary tumor location in the lower-extremity were identified and contacted via mail to complete an additional questionnaire. Participants completed the Reintegration into Normal Living Index (RNL) to evaluate global function (maximum score of 22), daily function (maximum score of 16) and self perception (maximum score of 6).<br />Results: Survivors reported high levels of global function with an adjusted mean overall RNL index score of 20.6 (SE 0.14), mean daily function score of 15.0 (SD 0.10) and mean self perception score of 5.6 (SE 0.05). While female gender and increasing age were associated with lower RNL scores, the magnitude of difference is of questionable clinical significance. Global function was only moderately correlated with physical performance (r = 0.56) and QOL (r = 0.59).<br />Discussion: Based upon the RNL index, the vast majority of long-term survivors of childhood lower extremity bone tumors adapt well to their environment.<br />Implications for Cancer Survivors: While some long-term survivors of lower-extremity bone tumors may report measurable limitations in physical performance and quality of life, the majority do not report moderate or severe difficulties with social integration.
- Subjects :
- Adolescent
Adult
Age of Onset
Bone Neoplasms epidemiology
Bone Neoplasms physiopathology
Child
Child, Preschool
Cohort Studies
Female
Humans
Infant
Lower Extremity physiopathology
Male
Middle Aged
Osteosarcoma epidemiology
Osteosarcoma physiopathology
Recovery of Function
Retrospective Studies
Sarcoma, Ewing epidemiology
Sarcoma, Ewing physiopathology
Sarcoma, Ewing rehabilitation
Surveys and Questionnaires
Young Adult
Bone Neoplasms rehabilitation
Lower Extremity pathology
Motor Activity physiology
Osteosarcoma rehabilitation
Self Concept
Survivors statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 1932-2267
- Volume :
- 3
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of cancer survivorship : research and practice
- Publication Type :
- Academic Journal
- Accession number :
- 19030995
- Full Text :
- https://doi.org/10.1007/s11764-008-0073-y