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Nomogram of fetal middle cerebral artery peak systolic velocity at 23-35 weeks of gestation in a Brazilian population: pilot study.
- Source :
-
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians [J Matern Fetal Neonatal Med] 2008 Oct; Vol. 21 (10), pp. 714-8. - Publication Year :
- 2008
-
Abstract
- Objective: To establish normative data for the peak systolic velocity of the middle cerebral artery (MCA-PSV) of fetuses in the second half of pregnancy using multiples of the median and percentile reference range.<br />Methods: A cross-sectional study was performed in 90 healthy fetuses at between 23 and 35 weeks of gestation. A bi-dimensional axial scan of the brain, including the thalami and cavitas septi pellucidi was obtained. The circle of Willis was visualized using color flow mapping. Pulsed-wave Doppler velocimetry of the MCA was performed close to the artery's origin, with a beam-vessel angle below 20 degrees . A table with the multiples of the median (MoM) of the MCA-PSV for each gestational age was generated and Pearson's correlation coefficient (r) was calculated. Regression modeling across gestational age was performed to obtain the reference values.<br />Results: There was a strong correlation between the MCA-PVS and gestational age (r = 0.70; p < 0.001). Values for the MCA-PSV for the following MoM were calculated: 1.0, 1.29, 1.50, and 1.55. The MCA-PSV 2.5(th) and 97.5(th) centiles ranged from 24.33 cm(2)/s to 78.36 cm(2)/s, respectively, between weeks 23 and 35.<br />Conclusions: A nomogram for the fetal MCA-PSV during the second half of pregnancy was generated.
- Subjects :
- Blood Flow Velocity
Brazil
Cross-Sectional Studies
Female
Gestational Age
Humans
Middle Cerebral Artery diagnostic imaging
Pilot Projects
Population
Pregnancy
Ultrasonography, Prenatal methods
Middle Cerebral Artery physiology
Nomograms
Pregnancy Trimester, Second physiology
Pregnancy Trimester, Third physiology
Ultrasonography, Prenatal statistics & numerical data
Subjects
Details
- Language :
- English
- ISSN :
- 1476-4954
- Volume :
- 21
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
- Publication Type :
- Academic Journal
- Accession number :
- 19012187
- Full Text :
- https://doi.org/10.1080/14767050802215243