Acute renal failure due to visceral leishmaniasis by Leishmania infantum successfully treated with a single high dose of liposomal amphotericin B.

Authors :: Beltrame A
Arzese A
Camporese A
Rorato G
Crapis M
Tarabini-Castellani G
Boscutti G
Pizzolitto S
Calianno G
Matteelli A
Di Muccio T
Gramiccia M
Viale P
Source :: Journal of travel medicine [J Travel Med] 2008 Sep-Oct; Vol. 15 (5), pp. 358-60.
Publication Year :: 2008
Abstract: We report a visceral leishmaniasis case in an immunocompetent immigrant with acute renal failure. Parasites were demonstrated in bone marrow, peripheral blood, and kidney samples. A collapsing focal segmental glomerulosclerosis was documented, which was successfully treated with a single infusion of 10 mg/kg liposomal amphotericin B.

Subjects :: Adult
Angola
Animals
Dose-Response Relationship, Drug
Glomerulonephritis drug therapy
Glomerulonephritis microbiology
Humans
Italy
Leishmania infantum isolation & purification
Leishmaniasis, Visceral complications
Male
Treatment Outcome
Acute Kidney Injury drug therapy
Acute Kidney Injury microbiology
Amphotericin B administration & dosage
Antiprotozoal Agents administration & dosage
Leishmaniasis, Visceral diagnosis
Leishmaniasis, Visceral drug therapy
Travel

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