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Antimicrobial activity of ethylenediaminedisuccinate metal complexes.
- Source :
-
Chemistry & biodiversity [Chem Biodivers] 2008 Oct; Vol. 5 (10), pp. 2156-2159. - Publication Year :
- 2008
-
Abstract
- It is shown that metal complexes of the biodegradable ligand ethylenediaminedisuccinic acid (edds) present antimicrobial activity towards fungi and bacteria. [Cd(edds)], in particular, is more toxic than free Cd2+ to Aspergillus niger, behaving as a 'Trojan Horse' in the facilitated delivery of the toxic metal into the fungus.
- Subjects :
- Anti-Infective Agents chemistry
Aspergillus niger drug effects
Cell Cycle drug effects
Cell Line
Humans
Metals, Heavy pharmacology
Organometallic Compounds chemistry
Pycnoporus drug effects
Staphylococcus aureus drug effects
Structure-Activity Relationship
Anti-Infective Agents pharmacology
Ethylenediamines chemistry
Metals, Heavy chemistry
Organometallic Compounds pharmacology
Succinates chemistry
Subjects
Details
- Language :
- English
- ISSN :
- 1612-1880
- Volume :
- 5
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Chemistry & biodiversity
- Publication Type :
- Academic Journal
- Accession number :
- 18972505
- Full Text :
- https://doi.org/10.1002/cbdv.200890196