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The discovery of equipotent PPARalpha/gamma dual activators.
- Source :
-
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2008 Dec 01; Vol. 18 (23), pp. 6251-4. Date of Electronic Publication: 2008 Oct 01. - Publication Year :
- 2008
-
Abstract
- We report the design and synthesis of equipotent PPARalpha/gamma dual agonists starting from selective PPAR alpha agonist 1. In vivo data for 7 in the Zucker fa/fa rat are presented.
Details
- Language :
- English
- ISSN :
- 1464-3405
- Volume :
- 18
- Issue :
- 23
- Database :
- MEDLINE
- Journal :
- Bioorganic & medicinal chemistry letters
- Publication Type :
- Academic Journal
- Accession number :
- 18947994
- Full Text :
- https://doi.org/10.1016/j.bmcl.2008.09.094