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Extradural thoracic spinal cord compression: unusual initial presentation of post-transplant lymphoproliferative disorder.
- Source :
-
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation [J Heart Lung Transplant] 2008 Oct; Vol. 27 (10), pp. 1165-8. - Publication Year :
- 2008
-
Abstract
- Post-transplant lymphoproliferative disorder (PTLD) is a serious complication after solid-organ transplantation. We report a lung transplant recipient presenting with lower limb weakness as a result of extradural cord compression from PTLD. Diagnosis was made by laminectomy of T-3 with partial removal of the epidural mass. Further treatment consisted of chemoradiotherapy. The patient recovered completely. To our knowledge, this is the first reported case of PTLD presenting with signs and symptoms of spinal cord compression. The differential diagnosis of spinal cord compression in a patient who has had a transplant should include primary presentation of PTLD.
- Subjects :
- Adult
Antineoplastic Combined Chemotherapy Protocols administration & dosage
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Cyclophosphamide administration & dosage
Doxorubicin administration & dosage
Emphysema etiology
Humans
Magnetic Resonance Imaging
Male
Prednisone administration & dosage
Radionuclide Imaging
Spinal Cord pathology
Spinal Cord Compression diagnosis
Spinal Cord Compression pathology
Thoracic Neoplasms diagnostic imaging
Thoracic Neoplasms drug therapy
Treatment Outcome
Vincristine administration & dosage
Emphysema surgery
Lung Transplantation adverse effects
Lymphoproliferative Disorders diagnosis
Postoperative Complications diagnosis
Spinal Cord Compression etiology
alpha 1-Antitrypsin Deficiency complications
Subjects
Details
- Language :
- English
- ISSN :
- 1557-3117
- Volume :
- 27
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation
- Publication Type :
- Academic Journal
- Accession number :
- 18926411
- Full Text :
- https://doi.org/10.1016/j.healun.2008.06.008