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235 cases of excessive daytime sleepiness. Diagnosis and tentative classification.
- Source :
-
Journal of the neurological sciences [J Neurol Sci] 1977 Jan-Feb; Vol. 31 (1), pp. 13-27. - Publication Year :
- 1977
-
Abstract
- A series of 235 consecutive patients refferred to the Stanford University Sleep Disorders Clinic with the complaint of excessive daytime sleepiness (EDS) were investigated extensively. A satisfactory final diagnosis involving a consistent syndrome or pathogenic process was made in all but 7 patients. In the course of this work a variety of tests, including prolonged polygraphic monitoring of multiple variables and CSF measurements before and after probenecid ingestion, were utilized. Different syndromes were confirmed (harmonious hypersomnia, subwakefulness syndrome); the definitions of others were clarified and extended (narcolepsy, drug dependency, periodic hypersomnia associated with menstruation, upper airway sleep apnea in children). Two new entities were tentatively identified (narcolepsy with sleep apnea, the neutral state syndrome). Narcolepsy and upper airway sleep apnea accounted for the majority of the cases (199). A strategic schema utilizing specific categories and frequency of occurrence in the case series is presented to improve the diagnosis of the complaint of excessive daytime sleepiness by the practicing physician. This case series was analysed in order to develop tentatively a meaningful nosology.
- Subjects :
- Adolescent
Adult
Aged
Apnea complications
Apnea diagnosis
Child
Child, Preschool
Depression diagnosis
Disorders of Excessive Somnolence cerebrospinal fluid
Disorders of Excessive Somnolence diagnosis
Electroencephalography
Female
Humans
Hydroxyindoleacetic Acid cerebrospinal fluid
Iatrogenic Disease
Male
Menstruation Disturbances diagnosis
Middle Aged
Narcolepsy complications
Narcolepsy diagnosis
Narcolepsy physiopathology
Sleep Wake Disorders classification
Sleep, REM
Substance-Related Disorders diagnosis
Syndrome
Terminology as Topic
Wakefulness
Sleep Wake Disorders diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 0022-510X
- Volume :
- 31
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of the neurological sciences
- Publication Type :
- Academic Journal
- Accession number :
- 188992
- Full Text :
- https://doi.org/10.1016/0022-510x(77)90003-x