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Chalcones and their potential role in inflammation.

Authors :
Kontogiorgis C
Mantzanidou M
Hadjipavlou-Litina D
Source :
Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2008 Oct; Vol. 8 (12), pp. 1224-42.
Publication Year :
2008

Abstract

Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches.

Details

Language :
English
ISSN :
1389-5575
Volume :
8
Issue :
12
Database :
MEDLINE
Journal :
Mini reviews in medicinal chemistry
Publication Type :
Academic Journal
Accession number :
18855737
Full Text :
https://doi.org/10.2174/138955708786141034