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Chalcones and their potential role in inflammation.
- Source :
-
Mini reviews in medicinal chemistry [Mini Rev Med Chem] 2008 Oct; Vol. 8 (12), pp. 1224-42. - Publication Year :
- 2008
-
Abstract
- Chalcones are a group of phenolic compounds which possess a wide variety of cytoprotective and modulatory functions. They have been shown to possess antioxidant, oxygen scavenging and anti-inflammatory properties in a variety of experimental systems and can trigger the intracellular cascade of protective pathways offering a promising stratagem for therapeutic applications. In this research we will review the anti-inflammatory effect of chalcone derivatives and new approaches.
- Subjects :
- Animals
Anti-Inflammatory Agents pharmacology
Antioxidants metabolism
Chemistry, Pharmaceutical methods
Drug Design
Free Radical Scavengers
Humans
Leukotriene B4 chemistry
Models, Biological
Models, Chemical
Neutrophils metabolism
Oxygen chemistry
Phenol chemistry
Chalcones pharmacology
Inflammation
Subjects
Details
- Language :
- English
- ISSN :
- 1389-5575
- Volume :
- 8
- Issue :
- 12
- Database :
- MEDLINE
- Journal :
- Mini reviews in medicinal chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 18855737
- Full Text :
- https://doi.org/10.2174/138955708786141034