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Molecular epidemiology of carbapenem-resistant Acinetobacter baumannii in New Caledonia.
- Source :
-
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases [Clin Microbiol Infect] 2008 Oct; Vol. 14 (10), pp. 977-81. - Publication Year :
- 2008
-
Abstract
- Carbapenem-resistant Acinetobacter baumannii (CR-Ab) ranked third, with a frequency of 24.8%, among 202 strains of multidrug-resistant bacteria isolated from clinical samples in the main hospital of New Caledonia in 2004. All CR-Ab isolates were analysed by isoelectric focusing, conjugation, pulsed-field gel electrophoresis and PCR for the presence of carbapenemase genes. Fifty CR-Ab isolates produced carbapenemase OXA-23. The isolates belonged to a single clone presenting several subtypes, suggesting an endemic situation. This study further illustrates the widespread prevalence of carbapenemase OXA-23-producing CR-Ab isolates in the South Pacific.
- Subjects :
- Acinetobacter baumannii chemistry
Acinetobacter baumannii genetics
Bacterial Proteins analysis
Bacterial Proteins genetics
Cluster Analysis
Conjugation, Genetic
DNA Fingerprinting
DNA, Bacterial genetics
Electrophoresis, Gel, Pulsed-Field
Genotype
Humans
Isoelectric Focusing
New Caledonia epidemiology
Polymerase Chain Reaction
beta-Lactamases genetics
Acinetobacter Infections epidemiology
Acinetobacter Infections microbiology
Acinetobacter baumannii classification
Acinetobacter baumannii drug effects
Anti-Bacterial Agents pharmacology
Carbapenems pharmacology
Drug Resistance, Bacterial
Molecular Epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1469-0691
- Volume :
- 14
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 18828857
- Full Text :
- https://doi.org/10.1111/j.1469-0691.2008.02068.x