One-pot reaction as an efficient method for rigid molecular tweezers.

Rigid molecular tweezers are compounds of increasing scientific interest. As the structural requirements for such compounds are highly specific, few types of these tweezers are thus far known. The preparation of examples of rigid large-pincered molecular tweezers based on bis Troger's bases derived from 1,4-benzenediamine is described. In addition, evidence is presented of the different binding abilities of the diastereoisomers of such compounds.