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The phylogenic expression of plasmolipin in the vertebrate nervous system.
- Source :
-
Neurochemical research [Neurochem Res] 1991 Feb; Vol. 16 (2), pp. 123-8. - Publication Year :
- 1991
-
Abstract
- Plasmolipin is a plasma membrane proteolipid is a major myelin membrane component (Cochary et al., 1990). In this study we report the phylogenic expression of plasmolipin in the vertebrate nervous system. Using Western blot analysis with polyclonal antibodies, we have analyzed membrane fractions, including myelin, from elasmobranchs, teleosts, amphibians, reptiles, birds and mammals. On the basis of immune detection, plasmolipin appears to be restricted to the mammalian nervous system. Comparison of the central and peripheral nervous systems of mammals showed only minor differences in the level of plasmolipin in these two regions. Within mammals, little quantitative differences were observed when rat, human and bovine membrane fractions were compared. The late evolutionary expression of plasmolipin which results in its restriction to mammals makes it unique among the (major) myelin proteins. The potential physiologic significance of these data are discussed.
- Subjects :
- Amphibians
Animals
Birds
Blotting, Western
Brain Chemistry
Cattle
Cell Membrane chemistry
Fishes
Humans
Mammals
Myelin Sheath chemistry
Myelin and Lymphocyte-Associated Proteolipid Proteins
Peripheral Nerves chemistry
Rats
Reptiles
Spinal Cord chemistry
Tissue Distribution
Membrane Proteins
Nerve Tissue Proteins
Nervous System chemistry
Phylogeny
Proteolipids analysis
Subjects
Details
- Language :
- English
- ISSN :
- 0364-3190
- Volume :
- 16
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Neurochemical research
- Publication Type :
- Academic Journal
- Accession number :
- 1881515
- Full Text :
- https://doi.org/10.1007/BF00965699