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Chitosan/polyethylene glycol diacrylate films as potential wound dressing material.
- Source :
-
International journal of biological macromolecules [Int J Biol Macromol] 2008 Dec; Vol. 43 (5), pp. 456-62. Date of Electronic Publication: 2008 Sep 03. - Publication Year :
- 2008
-
Abstract
- Michael addition reaction of Chitosan (CS) and polyethylene glycol diacrylate (PEGDA) was carried out successfully in acidic solution. Films with CS/PEGDA weight ratios from 100/0 to 0/100 in 10% increments were analyzed by Fourier transform infrared (FTIR) spectroscopy, Scanning Electron Microscope (SEM) and X-Ray Diffraction (XRD). Additionally, the films were characterized by measuring mechanical property, swelling property. The potential application of the CS/PEGDA film as wound dressing material was evaluated in vitro by using mouse fibroblasts (L929) as reference cell lines, indirect cytotoxicity assessment indicated that CS/PEGDA films were nontoxic to L929 cell.
Details
- Language :
- English
- ISSN :
- 0141-8130
- Volume :
- 43
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- International journal of biological macromolecules
- Publication Type :
- Academic Journal
- Accession number :
- 18809431
- Full Text :
- https://doi.org/10.1016/j.ijbiomac.2008.08.010