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[Diagnosis and therapy for penile cancer: a report of 46 cases with literature review].
- Source :
-
Ai zheng = Aizheng = Chinese journal of cancer [Ai Zheng] 2008 Sep; Vol. 27 (9), pp. 962-5. - Publication Year :
- 2008
-
Abstract
- Background & Objective: Penile cancer is an uncommon malignancy, which is mainly treated by surgery, radiation and chemotherapy. This study was to investigate reasonable curative methods for penile cancer.<br />Methods: Medical records of 46 patients with penile cancer in the Department of Urology, The First Affiliated Hospital of Sun Yat-sen University between Jan. 1996 to Jan. 2005 were analyzed retrospectively. Forty-four patients had squamous cell carcinoma, one had Paget disease, and one had verrucous carcinoma.<br />Results: Thirty-nine patients received partial penectomy, four received total penectomy and perineal urethrostomy, one Paget disease patient received lesion resection and skin grafting, two patients did not receive surgery. Nine out of 10 patients with positive lymph node received ilioinguinal lymphadenectomy, and five received pelvic lymphadenectomy. Forty-one cases were regularly followed up for one to 10 years. The 1-, 2-, 5- and 10- year survival rates were 95.1%, 95.1%, 82.9% and 31.7%, respectively. Prognosis of patients with pelvic lymph node metastasis was poor. Two patients who had pelvic lymph node metastasis died of lung metastasis within two years after surgery.<br />Conclusions: Partial penectomy is an appropriate and effective management for penile cancer. Lymph node metastasis is an important prognostic factor for penile cancer. Patients with ilioinguinal lymph node metastasis should receive lymphadenectomy as early as possible to improve the therapeutic effect. The prognosis is poor for patients with pelvic lymph node metastases.
- Subjects :
- Adult
Aged
Aged, 80 and over
Carcinoma, Squamous Cell pathology
Carcinoma, Squamous Cell therapy
Carcinoma, Verrucous pathology
Carcinoma, Verrucous surgery
Carcinoma, Verrucous therapy
Chemotherapy, Adjuvant
Follow-Up Studies
Humans
Lymph Node Excision
Lymphatic Metastasis
Male
Middle Aged
Paget's Disease, Mammary pathology
Paget's Disease, Mammary surgery
Paget's Disease, Mammary therapy
Penile Neoplasms pathology
Penile Neoplasms therapy
Radiotherapy, Adjuvant
Retrospective Studies
Survival Rate
Young Adult
Carcinoma, Squamous Cell surgery
Penile Neoplasms surgery
Penis surgery
Subjects
Details
- Language :
- Chinese
- Volume :
- 27
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Ai zheng = Aizheng = Chinese journal of cancer
- Publication Type :
- Academic Journal
- Accession number :
- 18799036