Back to Search
Start Over
Crystallographic investigations of the tryptophan-derived cofactor in the quinoprotein methylamine dehydrogenase.
- Source :
-
FEBS letters [FEBS Lett] 1991 Aug 05; Vol. 287 (1-2), pp. 163-6. - Publication Year :
- 1991
-
Abstract
- A model of tryptophan tryptophylquinone (TTQ), recently proposed by McIntire et al. (Science (1991) 252, 817-824) to be the prosthetic group of the quinoprotein methylamine dehydrogenase, has been compared with electron density maps of this dehydrogenase from Thiobacillus versutus and Paracoccus denitrificans. The comparison shows that the TTQ model can be neatly accommodated, providing strong supportive evidence that TTQ is indeed the cofactor for this group of quinoproteins.
- Subjects :
- Binding Sites
Hydrogen Bonding
Macromolecular Substances
Models, Molecular
Molecular Structure
Oxidation-Reduction
Tryptophan chemistry
X-Ray Diffraction
Indolequinones
Oxidoreductases Acting on CH-NH Group Donors chemistry
Paracoccus denitrificans enzymology
Quinones chemistry
Thiobacillus enzymology
Tryptophan analogs & derivatives
Subjects
Details
- Language :
- English
- ISSN :
- 0014-5793
- Volume :
- 287
- Issue :
- 1-2
- Database :
- MEDLINE
- Journal :
- FEBS letters
- Publication Type :
- Academic Journal
- Accession number :
- 1879526
- Full Text :
- https://doi.org/10.1016/0014-5793(91)80041-z