Issues in the design and interpretation of chronic toxicity and carcinogenicity studies in rodents: approaches to dose selection.

Authors :: Schafer KA
Sellers R
Barale-Thomas E
Source :: Critical reviews in toxicology [Crit Rev Toxicol] 2008; Vol. 38 (10), pp. 895-6; author reply 897-8.
Publication Year :: 2008

Subjects :: Animals
Dose-Response Relationship, Drug
Organ Size
Pathology, Clinical
Risk Assessment
Rodentia
Carcinogenicity Tests methods
Carcinogens toxicity
Drug-Related Side Effects and Adverse Reactions
Toxicity Tests, Chronic methods

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