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Male lupus: prevalence of IgA deficiency, 7S IgM and abnormalities of reticuloendothelial system Fc-receptor function.
Male lupus: prevalence of IgA deficiency, 7S IgM and abnormalities of reticuloendothelial system Fc-receptor function.
- Source :
-
Clinical and experimental rheumatology [Clin Exp Rheumatol] 1991 May-Jun; Vol. 9 (3), pp. 265-9. - Publication Year :
- 1991
-
Abstract
- Serological studies conducted on sera from a group of 31 male SLE patients revealed a 32% prevalence of 7S IgM and a 9.7% prevalence of IgA deficiency. Previous reports using similar methods indicated a higher (43-50%) prevalence of 7S IgM than was found in studies involving predominantly females with SLE (15-18%), and an overall prevalence of IgA deficiency ranging from 0.95% to 4.6%. Males resembled females in the prevalence of Fc-receptor specific reticuloendothelial system dysfunction, correlating with levels of circulating immune complex-like material and disease activity.
- Subjects :
- Antibodies, Antinuclear analysis
Antibodies, Antinuclear immunology
Antigen-Antibody Complex blood
Female
Humans
Immunoglobulin A immunology
Immunoglobulin M analysis
Lupus Erythematosus, Systemic blood
Lupus Erythematosus, Systemic physiopathology
Male
Mononuclear Phagocyte System physiology
Prevalence
Sex Characteristics
IgA Deficiency
Immunoglobulin M immunology
Lupus Erythematosus, Systemic immunology
Mononuclear Phagocyte System ultrastructure
Receptors, Fc physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0392-856X
- Volume :
- 9
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Clinical and experimental rheumatology
- Publication Type :
- Academic Journal
- Accession number :
- 1879085