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Male lupus: prevalence of IgA deficiency, 7S IgM and abnormalities of reticuloendothelial system Fc-receptor function.

Male lupus: prevalence of IgA deficiency, 7S IgM and abnormalities of reticuloendothelial system Fc-receptor function.

Authors :
Kaufman LD
Heinicke MH
Hamburger M
Gorevic PD
Source :
Clinical and experimental rheumatology [Clin Exp Rheumatol] 1991 May-Jun; Vol. 9 (3), pp. 265-9.
Publication Year :
1991

Abstract

Serological studies conducted on sera from a group of 31 male SLE patients revealed a 32% prevalence of 7S IgM and a 9.7% prevalence of IgA deficiency. Previous reports using similar methods indicated a higher (43-50%) prevalence of 7S IgM than was found in studies involving predominantly females with SLE (15-18%), and an overall prevalence of IgA deficiency ranging from 0.95% to 4.6%. Males resembled females in the prevalence of Fc-receptor specific reticuloendothelial system dysfunction, correlating with levels of circulating immune complex-like material and disease activity.

Details

Language :
English
ISSN :
0392-856X
Volume :
9
Issue :
3
Database :
MEDLINE
Journal :
Clinical and experimental rheumatology
Publication Type :
Academic Journal
Accession number :
1879085