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Crown ether ring-fused nucleosides: synthesis and conformational properties.

Authors :
Coppola C
D'Onofrio J
Di Fabio G
De Napoli L
Montesarchio D
Source :
Nucleic acids symposium series (2004) [Nucleic Acids Symp Ser (Oxf)] 2008 (52), pp. 667-8.
Publication Year :
2008

Abstract

We here describe the synthesis of a series of novel bicyclic ribonucleoside derivatives, with 18-crown-6 ether moieties attached via their ribose 2- and 3- positions, as first examples of crown ether ring-fused nucleosides, to be evaluated as antiviral and/or antitumoral agents.

Details

Language :
English
ISSN :
1746-8272
Issue :
52
Database :
MEDLINE
Journal :
Nucleic acids symposium series (2004)
Publication Type :
Academic Journal
Accession number :
18776556
Full Text :
https://doi.org/10.1093/nass/nrn337