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Some observations on detritylation in solid-phase oligonucleotide synthesis.

Authors :
Millar S
Yan HT
Sanghvi YS
Pon R
Source :
Nucleic acids symposium series (2004) [Nucleic Acids Symp Ser (Oxf)] 2008 (52), pp. 311-2.
Publication Year :
2008

Abstract

The quality of oligodeoxyribonucleotides prepared by solid phase synthesis under different acid treatment time was compared. Much shorter acid delivery time did not lead to significant decrease of the full length products.

Details

Language :
English
ISSN :
1746-8272
Issue :
52
Database :
MEDLINE
Journal :
Nucleic acids symposium series (2004)
Publication Type :
Academic Journal
Accession number :
18776378
Full Text :
https://doi.org/10.1093/nass/nrn157