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[Prevalence of epithelial squamous cell abnormalities and associated factors in women of a rural town of Colombia].
- Source :
-
Biomedica : revista del Instituto Nacional de Salud [Biomedica] 2008 Jun; Vol. 28 (2), pp. 271-83. - Publication Year :
- 2008
-
Abstract
- Introduction: In spite of implementation of cytology-based cervical cancer screening in Colombia, mortality rates remain stable. The description of factors associated to cervical pre-neoplasic lesions is needed to establish strategies for mortality prevention.<br />Objective: The prevalence of epithelial squamous cell abnormalities was determined to explore the association of cytology abnormalities with described risk factors.<br />Materials and Methods: This population-based, cross-sectional study included 739 women randomly selected by age. A validated face-to-face questionnaire and conventional cervical cytology were used to collect the information. To establish the association between cervical abnormalities and some qualitative variables, the independent chi squared test was used. We also calculated prevalence ratio with their 95% confidence intervals. A logistic regression model was used to explore variables that potentially explain cytology abnormalities.<br />Results: The prevalence of squamous cell abnormality was 15.8%. Among women with abnormal cytology, 10% presented atypical squamous cells of undetermined significance, 3.9% low grade squamous intra-epithelial lesion and 1.9% high grade squamous intra-epithelial lesion. The adjusted logistical regression analysis showed that history of sexual transmitted disease, two or more sexual partners during entire life and previous abnormal cytology were associated with cytology abnormalities.<br />Conclusion: The relation of epithelial squamous cell abnormalities with sexual behavior history reflexes the link between human papiloma virus infection and cervical cancer pre-neoplasic lesions. The frequency of use and knowledge about the purpose of cytology were factors that suggested other diagnostic limitations such as quality of cervical cytology or barriers to access health care. These latter factors may be the underlying basis for the high cervical cancer mortality rates.
- Subjects :
- Adolescent
Adult
Aged
Aged, 80 and over
Colombia epidemiology
Cross-Sectional Studies
Diagnosis, Differential
Female
Humans
Middle Aged
Multivariate Analysis
Neoplasms, Squamous Cell mortality
Neoplasms, Squamous Cell prevention & control
Sexual Behavior
Surveys and Questionnaires
Uterine Cervical Neoplasms mortality
Uterine Cervical Neoplasms prevention & control
Epithelial Cells pathology
Neoplasms, Squamous Cell epidemiology
Neoplasms, Squamous Cell pathology
Uterine Cervical Neoplasms epidemiology
Uterine Cervical Neoplasms pathology
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0120-4157
- Volume :
- 28
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Biomedica : revista del Instituto Nacional de Salud
- Publication Type :
- Academic Journal
- Accession number :
- 18719718