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Molecular characterization of Echinococcus granulosus in Tunisia and Mauritania by mitochondrial rrnS gene sequencing.
- Source :
-
Parassitologia [Parassitologia] 2007 Dec; Vol. 49 (4), pp. 239-46. - Publication Year :
- 2007
-
Abstract
- Cystic hydatid disease is a zoonotic parasitic disease caused by the cestode Echinococcus granulosus and represents a major public health problem in many countries around the world, including North Africa. E. granulosus exists as a series of genetic variants or strains which differ in a wide variety of criteria that impact on the epidemiology, pathology and control of cystic hydatid disease. Nucleotide sequencing of the mitochondrial rrnS gene was here used to characterize 38 E. granulosus isolates collected from different regions and hosts in Tunisia and Mauritania. The results obtained reveal a significant genetic differentiation between E. granulosus hydatid cysts identified as belonging to the G1 genotype and to the G6/G7 cluster using the rrnS gene as marker, and indicate the circulation of the common sheep strain (G1) in all host species from Tunisia and the camel/pig strain cluster (G6/G7) in camel from Mauritania. Other investigations, using this method, are necessary for further genetic analysis of a wider range of isolates from different host species in order to more fully understand the genetic structure of E. granulosus populations and their transmission dynamics in this and neighbouring African countries.
- Subjects :
- Animals
Base Sequence
Camelus parasitology
Cattle
Cattle Diseases epidemiology
DNA, Helminth genetics
DNA, Mitochondrial genetics
DNA, Ribosomal genetics
Echinococcosis epidemiology
Echinococcosis parasitology
Echinococcus granulosus classification
Echinococcus granulosus isolation & purification
Genes, rRNA
Genotype
Mauritania epidemiology
Molecular Sequence Data
Polymerase Chain Reaction
RNA, Helminth genetics
RNA, Ribosomal, 18S genetics
Ribotyping
Sequence Alignment
Sequence Homology, Nucleic Acid
Sheep parasitology
Sheep Diseases epidemiology
Tunisia epidemiology
Cattle Diseases parasitology
Echinococcosis veterinary
Echinococcus granulosus genetics
Sheep Diseases parasitology
Subjects
Details
- Language :
- English
- ISSN :
- 0048-2951
- Volume :
- 49
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Parassitologia
- Publication Type :
- Academic Journal
- Accession number :
- 18689235