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Four-component benzyne coupling reactions: a concise total synthesis of dehydroaltenuene B.

Authors :
Soorukram D
Qu T
Barrett AG
Source :
Organic letters [Org Lett] 2008 Sep 04; Vol. 10 (17), pp. 3833-5. Date of Electronic Publication: 2008 Aug 02.
Publication Year :
2008

Abstract

A four-component coupling reaction of 3,5-dimethoxybenzyne with 2-methyl-2-cyclohexenylmagnesium chloride, carbon dioxide, and iodine was utilized as a key step in the first total synthesis of dehydroaltenuene B.

Details

Language :
English
ISSN :
1523-7052
Volume :
10
Issue :
17
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
18672878
Full Text :
https://doi.org/10.1021/ol8015435