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Does electrospray ionization produce gas-phase or liquid-phase structures?
- Source :
-
Journal of the American Chemical Society [J Am Chem Soc] 2008 Aug 20; Vol. 130 (33), pp. 10842-3. Date of Electronic Publication: 2008 Jul 29. - Publication Year :
- 2008
-
Abstract
- Electrospray ionization of tyrosine from a 3:1 (v:v) CH3OH/H2O solution is found to afford an M - H ion which is a 70:30 mixture of phenoxide and carboxylate ions. This corresponds to the gas-phase equilibrium composition and not the liquid-phase proportions. In contrast, the carboxylate is produced as the dominant ion (approximately 95%) from anhydrous CH3CN and CH3CN/H2O mixtures. The addition of small amounts of CH3OH to the solvent, however, convert the M - H ion back into the gas-phase isomeric ratio. The isomeric structure therefore depends on the solvent system from which an ion is sprayed.
Details
- Language :
- English
- ISSN :
- 1520-5126
- Volume :
- 130
- Issue :
- 33
- Database :
- MEDLINE
- Journal :
- Journal of the American Chemical Society
- Publication Type :
- Academic Journal
- Accession number :
- 18661998
- Full Text :
- https://doi.org/10.1021/ja802088u