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A straightforward synthesis of tetrameric estrone-based macrocycles.
- Source :
-
Organic letters [Org Lett] 2008 Aug 21; Vol. 10 (16), pp. 3555-8. Date of Electronic Publication: 2008 Jul 23. - Publication Year :
- 2008
-
Abstract
- A straightforward approach to macrocycles having four estrone-derived nuclei by the sequential Cu-catalyzed Huisgen azide-alkyne cycloaddition-Glaser-Eglington Cu homocoupling has been developed. Due to its efficiency and simplicity, this sequence is useful for application to different natural product scaffolds.
Details
- Language :
- English
- ISSN :
- 1523-7052
- Volume :
- 10
- Issue :
- 16
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 18646766
- Full Text :
- https://doi.org/10.1021/ol801313g